Several conditions can impact the integrity and function of the BBB in children, including:
Infections: Conditions like meningitis and encephalitis can disrupt the BBB, allowing pathogens and inflammatory cells to enter the brain. Trauma: Head injuries can compromise the BBB, leading to increased permeability. Hypoxia: Insufficient oxygen supply can weaken the BBB, making it more permeable. Metabolic Disorders: Conditions such as phenylketonuria (PKU) can affect BBB function.
