What Challenges are Associated with Amplification and Sequencing in Newborns?
There are several challenges in applying amplification and sequencing techniques to newborns. One major challenge is the quality of the sample, as neonatal samples may be limited in quantity and quality. Ensuring that the amplification process does not introduce errors is also critical, as even small mistakes can lead to incorrect diagnoses. Furthermore, interpreting the vast amount of data generated by sequencing requires specialized expertise and bioinformatics tools, making it a complex and resource-intensive process.
