Nephrotoxicity in children can be caused by a variety of factors, including:
Medications: Certain drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs), aminoglycosides, and some chemotherapeutic agents, are known to be nephrotoxic. Infections: Severe infections and the use of certain antibiotics to treat them can lead to kidney damage. Contrast Agents: Used in imaging studies, these substances can sometimes cause nephrotoxicity, especially in children with preexisting renal conditions. Herbal Supplements: Some herbal medications contain nephrotoxic substances. Environmental Toxins: Exposure to heavy metals such as lead or mercury can also result in nephrotoxicity.