Neonatal jaundice typically arises from an imbalance between bilirubin production and elimination. Excess bilirubin can accumulate due to several factors, including:
- Physiological jaundice: Occurs in most newborns due to immature liver function. - Breastfeeding jaundice: Can occur in breastfeeding infants due to insufficient intake. - Hemolytic disorders: Conditions like Rh incompatibility or G6PD deficiency increase bilirubin production. - Infections: Sepsis or TORCH infections can impair bilirubin metabolism. - Genetic disorders: Disorders such as Crigler-Najjar syndrome affect bilirubin conjugation.
