Low WBC counts, known as leukopenia, can result from: - Infections: Severe infections, such as sepsis, can deplete WBC levels. - Bone Marrow Suppression: Conditions like aplastic anemia or chemotherapy treatments can reduce WBC production. - Nutritional Deficiencies: Deficiencies in vitamins and minerals, such as vitamin B12 and folate, can lead to low WBC counts. - Autoimmune Disorders: Conditions like systemic lupus erythematosus (SLE) can cause the body to attack its own WBCs.