The development of secondary sexual characteristics follows a predictable sequence:
In girls, the first sign is usually breast budding (thelarche), followed by the growth of pubic hair (pubarche), a growth spurt, and finally the onset of menstruation (menarche). In boys, the first sign is typically the enlargement of the testicles, followed by the growth of pubic hair, a growth spurt, and the deepening of the voice.
The progression through these stages can be assessed using the Tanner Stages, which provide a standardized way to evaluate physical development during puberty.