What are the Indications for Colchicine in Pediatrics?
Colchicine is primarily indicated for treating familial Mediterranean fever (FMF) in children. FMF is an inherited inflammatory disorder characterized by recurrent episodes of fever and serosal inflammation, such as peritonitis, pleuritis, and arthritis. Colchicine helps prevent these episodes and can also prevent long-term complications such as amyloidosis, which can lead to kidney damage. Besides FMF, colchicine is sometimes used in pediatric patients for other conditions, such as periodic fever syndromes and Behçet's disease, although these applications are less common and should be considered on a case-by-case basis.
