What Are the Challenges in Conducting Mechanistic Studies in Pediatrics?
Conducting mechanistic studies in Pediatrics presents unique challenges: 1. Ethical Considerations: Children are a vulnerable population, necessitating stringent ethical guidelines to protect their well-being. 2. Limited Sample Sizes: Pediatric studies often have smaller sample sizes, making it harder to achieve statistically significant results. 3. Informed Consent: Obtaining informed consent is more complex, requiring assent from the child and consent from guardians. 4. Longitudinal Studies: Understanding long-term effects requires extended follow-up periods, which can be logistically challenging.
