The causes of hydrops fetalis can be diverse and sometimes multifactorial. Common causes include:
- Chromosomal abnormalities, such as Turner syndrome and Down syndrome. - Congenital heart defects. - Infections, including parvovirus B19, cytomegalovirus, and syphilis. - Anemia, due to conditions like alpha-thalassemia. - Liver diseases. - Lymphatic abnormalities.