What Are the Applications of Single Cell Sequencing in Pediatrics?
1. Developmental Biology: SCS can elucidate the complex processes of cell differentiation and tissue development in children. This can help in understanding normal and abnormal development. 2. Pediatric Oncology: In childhood cancers, SCS can identify tumor heterogeneity, track tumor evolution, and uncover resistance mechanisms to therapy. 3. Rare Genetic Disorders: For conditions caused by mutations in a small number of cells, SCS can detect these rare mutations, facilitating early diagnosis and personalized treatment. 4. Immunology: SCS can profile immune cells to understand pediatric immune responses and autoimmune disorders.
