What Are the Applications in Pediatric Diagnostics?
1. Renal Diseases: Electron microscopy is often used to evaluate kidney biopsies in children. It can identify ultrastructural changes in the glomeruli, helping diagnose conditions like Alport syndrome and minimal change disease.
2. Genetic Disorders: Certain genetic conditions, such as Duchenne Muscular Dystrophy and Cystic Fibrosis, can be better understood by examining tissues at the microscopic level, revealing characteristic pathological changes.
3. Infectious Diseases: It has been instrumental in identifying viral particles, such as in cases of Herpes Simplex Virus infection, which may not be detectable by other means.
4. Mitochondrial Disorders: Electron microscopy can reveal abnormalities in the mitochondria, aiding in the diagnosis of mitochondrial myopathies and other related disorders.
