What Are the Administration and Dosage Guidelines?
Sapropterin is usually administered orally in the form of tablets or powder for oral solution. The initial dosage is typically based on the neonate's weight, often starting at 10 mg/kg/day. The dosage may be adjusted based on the patient’s response and tolerance. Regular monitoring of blood phenylalanine levels is essential to ensure the effectiveness of the treatment and to make any necessary dosage adjustments.