pharmacogenomics

What Are Some Examples of Pharmacogenomics in Pediatric Practice?

Some notable examples include:
Thiopurine Methyltransferase (TPMT) Testing: Used in children with leukemia to determine the appropriate dose of thiopurine drugs.
CYP2D6 Genotyping: Helps in understanding the metabolism of drugs like codeine, which can be dangerous in children who are ultra-rapid metabolizers.
SLCO1B1 Genotyping: Assists in identifying the risk of myopathy in children taking statins for hypercholesterolemia.

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