Several CYP enzymes are particularly important in pediatrics, including:
- CYP3A4: Involved in the metabolism of many drugs and increases in activity with age. - CYP2D6: Metabolizes a wide range of medications and exhibits significant genetic variability. - CYP2C9 and CYP2C19: Also involved in drug metabolism with genetic polymorphisms affecting their activity. - CYP1A2: Involved in the metabolism of certain drugs and environmental chemicals.
