What are Off-Label Uses and Why are They Common in Pediatrics?
Off-label use refers to the prescription of a drug for an age group, dosage, or condition that has not been specifically approved by regulatory agencies. In pediatrics, off-label use is relatively common due to the lack of clinical trials involving children for many medications. Physicians often rely on their clinical experience, existing literature, and expert guidelines when prescribing off-label. While this practice can be necessary, it underscores the importance of ongoing research and updated drug labels to ensure safety and efficacy.
