Gastrointestinal defects in neonates are congenital malformations or functional abnormalities of the gastrointestinal (GI) tract that are present at birth. These defects can affect the stomach, intestines, esophagus, liver, pancreas, or other parts of the digestive system. They can lead to complications such as feeding difficulties, malabsorption, and even life-threatening conditions if not addressed promptly.