1. Initial Assessment: Carefully assess the patient's respiratory status, including blood gases, lung compliance, and chest X-rays. 2. Ventilator Settings: Start with low tidal volumes and adjust PEEP based on the patient's oxygenation and lung mechanics. 3. Monitoring: Continuously monitor the patient’s response to ventilation, including blood gas analysis, oxygen saturation, and clinical signs of distress. 4. Adjustments: Make gradual adjustments to the ventilator settings based on the patient's evolving condition.