PRT can be administered through various routes depending on the protein and condition being treated:
1. Intravenous (IV) Administration: Commonly used for enzymes and clotting factors. This method allows for rapid delivery into the bloodstream. 2. Intratracheal Administration: Used for surfactant proteins in the treatment of RDS. The protein is delivered directly into the trachea to reach the lungs efficiently. 3. Subcutaneous Administration: Sometimes used for enzyme therapies, offering a slower but sustained release of the protein into the bloodstream.