Staging of neuroblastoma is crucial for determining the treatment plan and prognosis. The International Neuroblastoma Staging System (INSS) and the International Neuroblastoma Risk Group Staging System (INRGSS) are commonly used. The stages range from:
Stage 1: Localized tumor with complete gross resection Stage 2: Localized tumor with incomplete resection Stage 3: Unresectable unilateral tumor Stage 4: Disseminated disease to distant lymph nodes, bone marrow, liver, skin, or other organs Stage 4S: A special subset for children under 12 months with localized primary tumor and limited metastasis
