Pain assessment tools: Using tools like the Neonatal Infant Pain Scale (NIPS) or the Premature Infant Pain Profile (PIPP) to assess pain levels. Non-pharmacological methods: Techniques such as swaddling, non-nutritive sucking, and skin-to-skin contact. Pharmacological interventions: Administering appropriate analgesics and sedatives as needed. Multidisciplinary approach: Involving a team of healthcare providers to develop and implement a pain management plan.