How is indomethacin used in managing a Patent Ductus Arteriosus (PDA)?
A Patent Ductus Arteriosus (PDA) is a condition where the ductus arteriosus fails to close after birth. This can lead to heart failure and other complications. Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), is used to encourage the closure of the ductus arteriosus. It is most effective when administered within the first few days of life.