Determining the appropriate dose of heparin for neonates involves several factors:
1. Weight-Based Dosing: Dosages are often calculated based on the neonate's weight.
2. Monitoring: Regular monitoring of clotting parameters, such as the activated partial thromboplastin time (aPTT), is essential to ensure therapeutic levels.
3. Clinical Condition: The underlying condition requiring heparin therapy also influences the dosing regimen.