How Does CFTR Protein Dysfunction Affect Pediatric Patients?
In cystic fibrosis, mutations in the CFTR gene lead to the production of a dysfunctional protein. This results in thick, sticky mucus accumulating in various organs, including the lungs, pancreas, and digestive system. For pediatric patients, this can mean chronic respiratory infections, poor growth, and malnutrition, significantly affecting their quality of life.
