How Does Antibody Mediated Rejection Occur in Neonates?
AMR in neonates can occur primarily in two contexts: neonatal heart transplantation and maternal-fetal immunologic interactions. In the case of heart transplants, the neonate's immune system may recognize the donor heart as foreign and produce antibodies against it. In maternal-fetal cases, antibodies from the mother can cross the placenta and attack fetal tissues.