How Does Allelic Heterogeneity Impact Pediatric Disorders?
In pediatrics, allelic heterogeneity can significantly impact the diagnosis, treatment, and prognosis of genetic disorders. For instance, two children with cystic fibrosis may have mutations in different parts of the CFTR gene, leading to varying severities and complications. Recognizing allelic heterogeneity helps in tailoring personalized approaches to manage and treat affected individuals.
