How Do Pharmacokinetics and Pharmacodynamics Differ in Children?
Children are not simply small adults; their bodies process drugs differently. Pharmacokinetics (how the body absorbs, distributes, metabolizes, and excretes a drug) and pharmacodynamics (how the drug affects the body) can vary significantly based on age, weight, and developmental stage. For instance, neonates have different renal clearance rates compared to older children, affecting how antibiotics are dosed and administered.