How Do Epigenetic Factors Influence Gene Regulation?
Epigenetic factors such as DNA methylation, histone modification, and non-coding RNAs can influence gene regulation without altering the DNA sequence. These modifications can be heritable and are affected by environmental factors such as diet, stress, and exposure to toxins. In pediatrics, epigenetic changes can be critical in understanding conditions like childhood obesity, autism spectrum disorders, and asthma.