Minimizing off target effects involves several strategies: - Dose Adjustment: Tailoring doses based on age, weight, and organ function can reduce the risk of off target effects. - Monitoring: Regular monitoring for signs of adverse effects can allow for early intervention. - Alternative Therapies: Exploring non-pharmacological interventions or using drugs with a better safety profile can be safer options. - Patient Education: Educating parents and caregivers about potential side effects and what to watch for is crucial.