Bleeding Disorders: Aspirin's antiplatelet effects can increase the risk of bleeding disorders in newborns, including intracranial hemorrhage, particularly in preterm infants or those with underlying coagulation abnormalities.
Renal Impairment: Aspirin can affect renal function, leading to potential renal impairment in neonates. This is particularly concerning for preterm infants whose renal systems are not fully developed.