Diagnosis typically involves a combination of methods:
1. Physical Examination: To check for lumps or other unusual signs. 2. Imaging Studies: Such as X-rays, CT scans, MRI, and PET scans to visualize the tumor. 3. Laboratory Tests: Blood and urine tests to look for abnormal levels of certain substances. 4. Biopsy: A sample of the tumor tissue is taken and examined under a microscope. 5. Bone Marrow Aspiration and Biopsy: Particularly for diagnosing leukemias.