Newborn screening typically involves a few key steps: 1. Blood Test: A small blood sample is taken from the baby's heel (often referred to as a heel prick) and sent to a laboratory for analysis. 2. Hearing Test: This involves placing a small earpiece or microphone in the baby’s ear to check for hearing issues. 3. Pulse Oximetry: A sensor is placed on the baby’s skin to measure oxygen levels in the blood, which helps in detecting critical congenital heart defects.