Detecting abnormal epigenetic modifications typically involves advanced techniques such as:
DNA Methylation Profiling: Techniques like bisulfite sequencing are used to assess methylation patterns across the genome. Chromatin Immunoprecipitation (ChIP): Used to detect histone modifications and understand chromatin state changes. Microarray Analysis: Allows for the examination of gene expression patterns influenced by epigenetic changes. RNA Sequencing: Helps in identifying non-coding RNAs involved in gene regulation.
