How are Enterovirus Infections Diagnosed in Neonates?
Diagnosis of enterovirus infections in neonates typically involves a combination of clinical evaluation and laboratory tests. Common diagnostic approaches include:
Polymerase Chain Reaction (PCR): A highly sensitive and specific test that detects viral RNA in blood, cerebrospinal fluid (CSF), throat swabs, or stool samples. Viral Culture: Although less commonly used due to longer turnaround times, viral culture can isolate the virus from various bodily fluids. Serology: Detection of specific antibodies against enteroviruses in the blood can help confirm an infection, though this method is less effective in neonates due to their immature immune response.
