What is Isotretinoin?
Isotretinoin is an oral retinoid primarily used to treat severe
acne, particularly in cases that are resistant to other treatments. It is a potent derivative of
vitamin A and has powerful anti-inflammatory and comedolytic effects.
How is Isotretinoin Administered and Monitored?
Isotretinoin is taken orally, usually in a dosage based on the patient's weight. Regular follow-ups with the healthcare provider are necessary to monitor for side effects and efficacy. Blood tests are typically done monthly to check
liver function and lipid levels.
What Precautions Should be Taken?
Female patients must use effective
contraception due to the high risk of severe birth defects if isotretinoin is taken during pregnancy. The iPLEDGE program in the United States requires that patients, prescribers, and pharmacists follow strict guidelines to prevent fetal exposure.
How Long is the Treatment Duration?
The typical course of isotretinoin treatment lasts between 4 to 6 months. The duration may vary based on the patient's response to the medication and the severity of the acne.
What is the Long-Term Outlook for Patients on Isotretinoin?
Many patients experience long-term remission of severe acne after completing a course of isotretinoin. However, some may require additional treatments. Close follow-up with a healthcare provider is essential to manage any recurring symptoms and side effects.
