In pediatrics, prostaglandins are commonly used to keep the ductus arteriosus open in newborns who have congenital heart defects. The ductus arteriosus is a blood vessel that allows blood to bypass the lungs in utero, and it usually closes shortly after birth. In some congenital heart conditions, it is vital to keep this vessel open to ensure proper circulation and oxygenation. Prostaglandin E1 (PGE1) is often administered for this purpose.
