Immunoglobulin Replacement Therapy (IRT) involves the administration of exogenous immunoglobulins to patients who have a deficiency in their own antibody production. This therapy is critical for children with primary immunodeficiency diseases (PIDs) such as Common Variable Immunodeficiency (CVID), X-linked Agammaglobulinemia (XLA), and severe combined immunodeficiency (SCID).
