Several conditions can lead to elevated ALT levels in children:
1. Viral Hepatitis: Infections such as hepatitis A, B, and C can cause significant liver inflammation and elevate ALT levels. 2. Non-Alcoholic Fatty Liver Disease (NAFLD): Increasingly common in obese children, NAFLD can cause elevated ALT levels. 3. Medications: Certain medications, such as anticonvulsants and antibiotics, can cause liver toxicity and raise ALT levels. 4. Inherited Metabolic Disorders: Conditions like Wilson's disease and alpha-1 antitrypsin deficiency can lead to liver damage and elevated ALT. 5. Autoimmune Hepatitis: This is a condition where the body's immune system attacks liver cells, leading to elevated ALT levels.
