Treatment for SRNS often involves a multi-faceted approach. Immunosuppressive drugs like calcineurin inhibitors (e.g., cyclosporine, tacrolimus) and other medications such as mycophenolate mofetil or rituximab may be used. Supportive treatments focus on managing symptoms and may include diuretics for edema, ACE inhibitors or ARBs for proteinuria, and statins for hyperlipidemia.