What is NASH?
Non-Alcoholic Steatohepatitis (NASH) is a progressive liver disease characterized by inflammation and damage in the liver due to fat accumulation, not caused by alcohol consumption. It is a subset of
Non-Alcoholic Fatty Liver Disease (NAFLD), which also includes simple fatty liver.
Fatigue
Abdominal discomfort
Unexplained weight loss
Enlarged liver (hepatomegaly)
Clinical history and physical examination
Blood tests to check liver enzymes (
ALT and
AST)
Ultrasound or other imaging techniques to detect liver fat
Liver biopsy, considered the gold standard, to assess inflammation and fibrosis
How is NASH treated in children?
There is no specific medication approved for NASH, but treatment focuses on lifestyle changes and managing underlying conditions:
Encouraging a balanced diet rich in
fruits,
vegetables, and whole grains
Promoting regular physical activity
Monitoring and treating associated conditions like obesity, diabetes, and dyslipidemia
Regular follow-ups with a pediatric hepatologist
Maintaining a healthy weight
Adopting a nutritious diet low in processed foods
Engaging in regular physical activity
Regular health check-ups to monitor liver health
What is the prognosis for children with NASH?
The prognosis varies depending on the severity of the disease and how early it is diagnosed and managed. With appropriate lifestyle changes and medical care, many children can achieve significant improvement and prevent progression to more severe liver disease.
