Early Onset sepsis - Neonatal Disorders

What is Early Onset Sepsis?

Early onset sepsis (EOS) is a serious bloodstream infection that occurs in newborns within the first 72 hours of life. It is a significant cause of morbidity and mortality in the neonatal period. EOS is typically acquired from the mother during delivery and is often caused by bacteria such as Group B Streptococcus (GBS) and Escherichia coli.

What are the Risk Factors?

Several risk factors increase the likelihood of EOS in newborns. These include:
- Premature rupture of membranes (PROM) for more than 18 hours.
- Maternal colonization with GBS.
- Maternal fever during labor.
- Chorioamnionitis, an infection of the fetal membranes.
- Preterm birth (

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